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Importantly, these receptors have been located to have been activated by a wide range of endogenous opioids in a focus similar to that observed for activation and signaling of classical opiate receptors. In turn, these receptors had been uncovered to get scavenging activity, binding to and lowering endogenous levels of opiates obtainable for bindin
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Importantly, these receptors were being located to have been activated by an array of endogenous opioids in a focus comparable to that observed for activation and signaling of classical opiate receptors. Consequently, these receptors were being located to possess scavenging activity, binding to and reducing endogenous amounts of opiates accessible